1299 Racial, ethnic, and gender disparities in cutaneous t-cell lymphoma

Cutaneous T-cell lymphoma (CTCL) is a group of rare cancers skin-homing T-cells. Previous epidemiologic studies showed higher incidence rate, younger age onset, and worse overall survival in Black CTCL patients than White patients. We conducted retrospective study seen at Moffitt Cancer Center from 2010-2022 to investigate for racial, ethnic, gender disparities. identified 1013 with confirmed diagnosis by pathology. Patient characteristics included age, gender, race, clinical stage, date initial diagnosis, vital status, death/last follow-up, insurance payor time diagnosis. Consistent prior reports, presented more commonly men, >60 years old, early-stage disease (<IIB). onset (median 50) 64) (p<0.001). Hispanic also non-Hispanic Large cell transformation (LCT) occurred approximately 10% (n=93) 32% advanced stage (≧IIB). Importantly, we found that 1) male were likely develop LCT (OR 2.19; p=0.0023) 2) poorer compared (p=0.0068), shorter (p=0.037), death or last follow up (p=0.011). In conclusion, have earlier onset. Male are rapid progression death. Further research on socioeconomic environment, health care access can help understand